Enzo started his career in karting like many other drivers, starting in 2005. He made his professional karting debut in 2009. Fittipaldi scored highly in many championships like the 2009 Rotax Grand Nationals U.S.A. – Micro Max, where he placed 6th in a highly competitive championship.
Prior to starting junior Formulae, he raced in the Ginetta Junior championship for the first 7 rounds. Enzo drove for Douglas Motorsport. He accumulated 113 points meaning he finished in 18th position. In the standings, he finished behind Max Bird and finished ahead of Olli Caldwell. During this season, he also was invited to join the Ferrari Driver Academy alongside Marcus Armstrong, Antonio Fuoco, Guanyu Zhou, Giuliano Alesi, Callum Ilott, Robert Shwartzman, Gianluca Petecof and Charles Leclerc.
He then made his debut for single seaters in Italian Formula 4 and ADAC Formula 4. He was only a guest driver for ADAC Formula 4, competing in one round with Prema Powerteam during Nürburgring. In Italian Formula 4, Fittipaldi also drove for Prema, driving alongside Marcus Armstrong, Jüri Vips and Juan Manuel Correa. He earned 89 points, gaining 9th in the standings ahead of Kush Maini.
For the following year, he once again competed in Italian Formula 4 and ADAC Formula 4 with Prema Theodore Racing, but this time competing in the entire championship. For ADAC Formula 4, Enzo finished 3rd in the standings, gaining 223 points with a win and 9 podiums, finishing behind Lirim Zendeli and Liam Lawson. In comparison, Italian Formula 4 left him 303 points in the standings, earning 7 wins and 12 podiums. This meant he finished 1st in the standings ahead of Leonardo Lorandi.
Fittipaldi ended up staying another year with Prema but this time racing in the new championship, Formula Regional European. Here, he raced with Frederik Vesti and Olli Caldwell. During the season, he won two races in Circuit Paul Ricard and Imola. With 13 podiums and 2 wins under his name, he finished 2nd in the standings and 2nd in the rookie standings, both behind Danish teammate Frederik Vesti.
FIA Formula 3 Championship
Enzo started his debut with the Formula 3 machinery with the Sauber Junior Team by Charouz in the Macau Grand Prix during the 2019 season. Although he qualified last, he raced to 14th position ahead of Sebastián Fernández. However, for the main race, he was outscored by Sebastián and finished in 16th position.
For the 2020 season, he will be driving in the Formula 3 Championship, driving with Jake Hughes and Jack Doohan. Backed by the Ferrari Driver Academy, he will support red colours on his car, whilst Jake has blue and Jack has orange.